There are hundreds of elephants within the park. Antelope include kudu, sable and bushbuck. There are leopards and hyaena. Lions were reintroduced to the area in 2013, and Black rhino before them. Birdlife is exceptionally varied which makes Liwonde a true top birdwatching locations. Most notably are the water-associated birds as the African fish eagle, the pied kingfisher, the saddle-billed stork and goliath heron. This national park is one of the best places anywhere to seek out some of the rarer water birds among them Pel’s fishing owl - often seen at dusk along the river’s edge, red-necked falcon and palm-nut vulture. The river attracts fish eagles, whilst weaver birds build their nests in the thin woodland.
Liwonde National Park is dominated by mopane woodland, with the mopane trees creating a canopy 12 metres high. The landscape also is rich with other species including the spectacular baobab trees and the poetic fever trees.